A new review investigates the effects of avocados on different components of metabolic syndrome, which is a clustering of risk factors including high blood sugar, cholesterol, blood pressure, and body mass index. These risk factors lead to an increased risk of type 2 diabetes and cardiovascular disease.
According to studies reported in the literature, avocados have the most beneficial effects on lipid profiles, with changes to LDL-cholesterol, HDL-cholesterol, triglycerides, total cholesterol, and phospholipids.
In a randomized crossover study, 12 women with T2DM received two different diets. One received a high monounsaturated fatty acids diet (including oleic acid from avocado and olive oil) and the other received a high-complex carbohydrates diet for 4 weeks. The results showed that the first diet maintained an adequate glycemic control and offered a good management alternative. Another randomized clinical trial, investigated on 26 healthy overweight subjects, revealed that consumption of half of a Hass avocado significantly reduced the blood insulin and glucagon-like peptide-1 levels. It was concluded that D-mannoheptulose may be responsible for hypoglycemic effect by glycolysis decline via hexokinase inhibition and weight control via appetite reduction. In addition, the results of Wien et al. investigation on healthy overweight adults showed that avocado in lunch meal attenuated the rise in postprandial blood insulin levels 30 min after start of the lunch meal and diminished the desire to eat as compared with the avocado-free control which could be because of its anti-obesity effect
The peel, seed, flesh, and leaves of avocados have differing effects on components of metabolic syndrome.
“Avocado is a well-known source of carotenoids, minerals, phenolics, vitamins, and fatty acids,” wrote the authors of the Phytotherapy Research review. “The lipid- lowering, antihypertensive, antidiabetic, anti-obesity, antithrombotic, antiatherosclerotic, and cardioprotective effects of avocado have been demonstrated in several studies.”
In this review, several studies were summarized different in vivo, in vitro and clinical studies accomplished by researchers around the world to find out the role of peel, seed, flesh, and leaves of avocado in metabolic syndrome. Most of these studies have suggested the use of this plant in the diet, on a daily basis, to manage different components of metabolic syndrome.